![]() ![]() Most anti-aging strategies either completely backfire on skin like mine or offer some temporary Replenishing this vital molecule is likely to have a myriad of marked benefits for aging skin.īoth products are extremely light, quickly absorbed, and leave no residue behind. Remodeling, cell adhesion, immune function, and growth factor responsiveness. With age, our levels of heparan sulfate decline, and our skin sags, collagen becomes less organized, and wounds heal more slowly. Heparan sulfate also plays a major role in tissue For instance, heparan sulfate can bind and interact with extracellular matrix molecules, collagen types I, III, IV, and V, growth factors and cytokines (the basis of stem cell skin care lines), elastase, and much more (see Gallo, 2000). Heparan sulfate is present in all layers of skin and-due to its key actions in skin health and wound repair–has been termed a “master molecule” for skin. However, despite HA’s renown, it actually has far less biological activity than another GAG, heparan sulfate. ![]() When it comes to GAGs, most consumers will be most familiar with hyaluronic acid (HA), which holds a great deal of water, leading to its inclusion in countless skin care products as well as injectable fillers. ![]()
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